RAB1124
Sigma-Aldrich

Mouse Gremlin-1 ELISA Kit

Nacres: NA.32
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Properties

Properties
assay range inter-assay cv: <
astm d 2162 12%
intra-assay cv: <
astm d 301-56 10%
sensitivity: 0.8 ng/ml
Description Mouse Gremlin-1 ELISA Kit for cell culture supernatants, plasma, and serum samples
determination of p-n colorimetric
glass tube o.d. × l mouse ... Grem1(23892)
insert h × w sample type plasma
sample type serum sample(s)
sample type cell culture supernatant(s)
MDM Code RAB1124-1KT
Material Number RAB1124
Business Unit 34
CAS Number 0

Description

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

Gremlin-1 (GREM1) has a role in embryogenesis. It also has a role in cell functions during development. GREM1 acts as an antagonist of bone morphogenetic proteins (BMP). The protein influences chondrogenesis, outgrowth and apoptosis in limb bud development and has a role in kidney formation. It inhibits the activity of BMP2 and BMP4. GREM1 is involved in angiogenesis, bone formation, bone mass and pulmonary hypertension. Knockout of this gene in mice leads to developmental abnormalities.

General description

Gremlin-1 (GREM1) is part of the secreted, cysteine knot DAN family of bone morphogenetic protein antagonists. It has a molecular weight of 24–26kDa.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word <

Packaging

I>

Physical form

sample<

Physical properties

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Preparation Note

in the text box provided for lot number.

SAFETY INFORMATION

Signal Word

Warning

RIDADRRIDADR

WGK Germany

WGK 3

Flash Point (F)

Not applicable

Flash Point (C)

Not applicable

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

TECHNICAL SERVICE

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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