P7000
Sigma-Aldrich

Pepsin from porcine gastric mucosa

Synonyms English:

Pepsin A

Mdl No: MFCD00081840
CAS Number: 9001-75-6
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Properties

Properties
applications diagnostic assay manufacturing
biological source Porcine gastric mucosa
Description Pepsin from porcine gastric mucosa powder, >=250 units/mg solid
form powder
gene information pig ... LOC396892(396892)
MDM Code P7000-100G
Material Number P7000
Business Unit 760
CAS Number 9001-75-6

Description

Analysis Note

Optimum pH is 2-4. Active in 4 M urea and 3 M guanidine HCl. Stable at 60 

Antibody Adsorbant

°C. Pepsin is irreversibly inactivated at pH 8.0 - 8.5.

Biochem/physiol Actions

Pepsin cleavage can be used to produce F(ab′

Caution

)2 fragments of antibodies. pepsin at www.sigma-aldrich.com/enzymeexplorer.

Cell Line Description

Preferential cleavage: hydrophobic and aromatic residues in P1 and P1′ postitions. Cleaves Phe-Val, Gln-His, Glu-Ala, Ala-Leu, Leu-Tyr, Tyr-Leu, Gly-Phe, Phe-Phe and Phe-Tyr bonds in the β chain of insulin

Physical form

View more information on pepsin at www.sigma-aldrich.com/enzymeexplorer.

SAFETY INFORMATION

GHS07,GHS08

Signal Word

Danger

H315 - H319 - H334 - H335

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

RIDADRRIDADR

WGK Germany

WGK 1

Flash Point (F)

Not applicable

Flash Point (C)

Not applicable

Target Organs

Respiratory system

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

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