N4126
Sigma-Aldrich

Nicotinic acid

Empform:

C6H5NO2

Synonyms English:

3-Picolinic acid

Nacres: NA.25
Mdl No: MFCD00006391
Fw: 123.11
Pubchem Substance Id: 24897668
CAS Number: 59-67-6
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Properties

Properties
assay
assay range 98%
blade diam. synthetic (organic)
coloring against scale white to off-white
Description Nicotinic acid >=98%
format powder
glass tube l × o.d. × i.d. human ... CYP1A2(1544)
rat ... Chrnb2(54239)
inchi key 1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H(H89)
indiff. to chromic acid PVNIIMVLHYAWGP-UHFFFAOYSA-N
MDM Code N4126-5G
Material Number N4126
Business Unit 777
Shipping Mode AP
MRP Type PD
Local HS Code 29362900
EUD YES
Legacy SIGMA
Shelf Life 0
Plant 6311
Sales Org 6304
EUD Documents Needed 0
CAS Number 59-67-6

Description

Application

Nicotinic acid has been used:
  • as a component of the MS vitamins stock solution
  • for the detection of siderophores in Escherichia coli bacterial culture
  • as a component of the holidic medium for adult Drosophila .

Biochem/physiol Actions

Niacin is involved in the production of nicotinamide adenine dinucleotide (NAD+), which is used in the adenine triphosphate (ATP) production in mitochondrial oxidative phosphorylation. It also decreases hepatic production of very-low density lipoproteins (VLDL), and apolipoprotein B (apo-B). Niacin deficiency leads to pellagra.

General description

Nicotinic acid is also known as vitamin B3 or Niacin. It is a water soluble vitamin. Niacin can be either synthesized within the body or can be obtained from dietary sources.

SAFETY INFORMATION

Signal Word

Warning

P305 + P351 + P338

RIDADRRIDADR

WGK Germany

WGK 1

Flash Point (F)

379.4 °F - closed cup

Flash Point (C)

193 °C - closed cup

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

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