H7039
Sigma-Aldrich

3-Hydroxy-3-methylglutaryl-CoA reductase human

Synonyms English:

HMGCoA Reductase

Nacres: NA.54
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Properties

Properties
assay
assay range 90% (SDS-PAGE)
Description 3-Hydroxy-3-methylglutaryl-CoA reductase human solution
format solution
glass tube l × o.d. × i.d. human ... HMGCR(3156)
MDM Code H7039-250UG
Material Number H7039
Business Unit 760
Shipping Mode AP
MRP Type PD
Local HS Code 35079000
EUD NO
Legacy SIGMA
Shelf Life 0
Plant 6311
Sales Org 6304
EUD Documents Needed 0

Description

Application

3-Hydroxy-3-methylglutaryl-CoA reductase human has been used:
  • in anti-HMGCR enzyme linked immunosorbent assay (ELISA)
  • as an antigen to measure anti-HMGCR antibodies by blot analysis
  • in HMG-CoA reductase activity assays
  • as an antigen to compare in-house antigen via sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE)/western blot

Biochem/physiol Actions

Hydroxy-3-methylglutaryl-CoA reductase catalyzes the committed step in cholesterol biosynthesis.

Physical form

Supplied as a solution containing 250 μg protein in 50 mM Tris pH 7.5, with 5 mM DTT, 1:200 Protease Inhibitor Cocktail (Catalog Number P8340) and 50% (w/v) glycerol.

Physical properties

Consists of the HMG CoA reductase catalytic domain fused to GST protein.

Unit Definition

One unit will convert 1.0 μ

Warning

mole of NADPH to NADP+ per minute at 37 °C.

SAFETY INFORMATION

Signal Word

RIDADRRIDADR

WGK Germany

WGK 1

Flash Point (F)

Not applicable

Flash Point (C)

Not applicable

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

TECHNICAL SERVICE

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