G11950
Sigma-Aldrich

Guanine

Empform:

C5H5N5O

Synonyms English:

2-Amino-1,7-dihydro-6H-purin-6-one; 2-Amino-6-hydroxypurine; 2-Aminohypoxanthine

Nacres: NA.22
Mdl No: MFCD00071533
Fw: 151.13
Pubchem Substance Id: 24895050
CAS Number: 73-40-5
Grouped product items
SKU Pack Size Availability Price Quantity
Request a Bulk Order Check Availability

Properties

Properties
assay 98%
Description Guanine 98%
inchi 1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H(H467891011)
inchi key UYTPUPDQBNUYGX-UHFFFAOYSA-N
MDM Code G11950-10G
Material Number G11950
Business Unit 774
Shipping Mode AP
MRP Type PD
Local HS Code 29335990
EUD NO
Legacy SIGMA
Shelf Life 0
Plant 6311
Sales Org 6304
EUD Documents Needed 0
CAS Number 73-40-5

Description

Application

Guanine is suitable reagent used to investigate the mechanism of electrochemical oxidation of guanine and adenine using a glassy carbon microelectrode and cyclic and differential pulse voltammetry. It may be used in the preparation of mixed-sequence peptide nucleic acid (PNA) monomers.

General description

Adenine, cytosine, thymine and guanine are the four main nucleobases found in nucleic acids DNA and RNA. Guanine is a purine derivative. It is reported to assemble into square-planar groups that resemble macrocycles, in which the bases interact via hydrogen bonds. In DNA and RNA, stretches of guanine bases are reported to form stable four stranded helices in the presence of sodium or potassium ions. The electrochemical oxidation of guanine has been studied in aqueous media at various carbon electrodes. It reacts with peroxynitrite under physiological conditions to afford 8-nitroguanine.

SAFETY INFORMATION

Signal Word

Warning

H315 - H319 - H335

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

RIDADRRIDADR

WGK Germany

WGK 3

Flash Point (F)

Not applicable

Flash Point (C)

Not applicable

Target Organs

Respiratory system

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

TECHNICAL SERVICE

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Welcome to Merck Ecommerce (Beta). During this Beta phase, you may encounter occasional broken function, layout and issues. ×