32417
Supelco

Natamycin

Empform:

C33H47NO13

Synonyms English:

Pimaricin

Nacres: NA.24
Mdl No: MFCD00135085
Fw: 665.73
Pubchem Substance Id: 329754196
CAS Number: 7681-93-8
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Properties

Properties
applications cleaning products
cosmetics
food and beverages
personal care
Description Natamycin VETRANAL(R), analytical standard
format neat
grade analytical standard
inchi 1S/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(4247-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-911-1318-2527-303235-3638-3942H1014-1734H21-2H3(H4041)/b4-3+7-5+8-6+11-9+13-12+/t18-19-20+21+22+23-24-25+27-28+29-30+32+33-/m1/s1
inchi key NCXMLFZGDNKEPB-FFPOYIOWSA-N
MDM Code 32417-50MG
Material Number 32417
Business Unit 533
Shipping Mode AP
MRP Type PD
Local HS Code 29419000
EUD NO
Legacy SIGMA
Shelf Life 0
Plant 6311
Sales Org 6304
EUD Documents Needed 0
CAS Number 7681-93-8

Description

Application

Natamycin may be used as an analytical reference standard for the quantification of the analyte in wine samples using high-performance liquid chromatography coupled to electrospray ionization in positive mode high resolution mass spectrometry (HPLC-ESI-HR-MS) and reversed-phase high-performance liquid chromatography-tandem mass spectrometry technique (UHPLC-MS/MS).

Biochem/physiol Actions

An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane

General description

Natamycin is a polyene antibiotic that generally finds application as an antifungal agent as it lacks development of resistance and has a broad spectrum of activity. However, its mode of action is yet unclear, direct binding and isothermal titration calorimetry studies has revealed that natamycin binds specifically to ergosterol present in model membranes.

SAFETY INFORMATION

Signal Word

RIDADRRIDADR

WGK Germany

WGK 3

Flash Point (F)

Flash Point (C)

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

TECHNICAL SERVICE

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